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New Study Uncovers Prevention Factors for Kidney Disease in Children

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Wednesday, March 25, 2015   

INDIANAPOLIS - New hope is on the horizon for children suffering from chronic kidney disease, thanks to the results of a new study that, for the first time, identifies some of the factors that can lead to kidney failure.

Pediatric nephrologist Dr. Bradley Warady at Children's Mercy Hospital in Kansas City, Mo., was the co-principal investigator on the study, which looked at nearly 500 kids with chronic kidney disease over 10 years. Many people don't realize, he said, that kidney disease can have a profound effect on a child's growth and development.

"Not only can you develop an inability to remove waste products and fluids," he said, "but you may be very short, you may have poor nutrition, you may have poor growth - so it impacts the global development of the child."

Warady said the risk factors investigators uncovered - including high blood pressure, anemia and protein loss - are treatable, and the hope is that addressing those issues will keep kidney disease from progressing so that children can avoid having to go through dialysis or even transplants.

Chronic kidney disease is not as common in children as it is in adults, Warady said, but it can be much more challenging to treat. The good news, he said, is that many of the underlying issues investigators uncovered can be successfully managed.

"If we can do that," he said, "maybe - I can't say for sure yet, but maybe - we have a chance of altering the progression or the worsening of chronic kidney disease."

The study, which was funded by the National Institutes of Health, is published in the National Kidney Foundation's American Journal of Kidney Diseases and is online at ajkd.org.


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