SEATTLE – An at-home test could be a major breakthrough for screening cervical cancer in women, according to a new study.

Researchers at the University of Washington and Kaiser Permanente Washington teamed up on a study involving 20,000 women who weren't getting regular screening.

Half were mailed home tests for human papillomavirus, or HPV – the virus that can cause cervical cancer. The other half received just standard care such as annual reminders for preventive screenings.

Diana Buist, a senior investigator at the Kaiser Permanente Washington Health Research Institute, says the mailed tests increased screening rates by 50%.

"Which is a lot,” she states. “The women that we tested the home test kit on were under-screened, which means that they were overdue for cervical cancer screening, and that's about one in four women in the United States. And 50% of cervical cancers are diagnosed in those women."

About 12,000 women are diagnosed with cervical cancer each year.

Buist says screening rates are declining across the country. She notes home-based testing has been offered in other countries, but this is the first trial of home kits in the U.S.

Rachel Winer, an epidemiology professor at the UW School of Public Health and lead author of this research, says studies have shown there's no difference between the results from at-home tests and ones performed by physicians.

She says health professionals are looking to overcome the barriers to screening more women.

"It can be hard to find time to come in, difficulties taking time off of work or finding child care or transportation,” she points out. “In addition, many women have had negative experiences with cervical cancer screening or pelvic exams in general."

Winer says not all the women who tested positive followed up and so the next step will be figuring out how to get them to see a physician.

But she notes 88% of women who did the home kit tested negative.

"That means that if you were to roll this out, only 12 out of 100 women who did this would actually need to come in for additional follow-ups,” she stresses. “So you're saving the need for that clinic visit for 88% of women."

This week is Crohn's and Colitis Awareness Week, shedding light on what some call an invisible disease.

Crohn's disease and ulcerative colitis are also known as inflammatory bowel disease, and they affect a person's food choices and many other aspects of life.

Ryan Boyce - executive director of the Northwest chapter of the Crohn's and Colitis Foundation - said symptoms include abdominal pain, rectal bleeding and diarrhea.

But Boyce said many suffer in silence because those symptoms aren't usually visible.

"It's a difficult disease to diagnose and it's very common for folks to really struggle with these symptoms for a while," said Boyce, "before they get properly diagnosed and can begin a treatment path to help improve their health."

A recent study found about one in 100 Americans has been diagnosed with inflammatory bowel disease, or IBD.

Boyce said there's no cure for the disease, although there are a few approaches that can alleviate symptoms, such as medication and changes to a person's diet.

"The unique thing with IBD is that it impacts everyone a little bit differently," said Boyce. "So, there's not one set strategy and plan, or a blueprint if you will, that if everyone follows then it kind of limits symptoms. There's just so much variance with the disease."

Boyce said there have been major strides in the search for solutions for this affliction.

"What we're really trying to do is find cures," said Boyce, "and cures, plural, because it will take more than one cure depending on the disease and the treatment - and pushing toward that."




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November has been Diabetes Awareness Month - but heading into the holidays, people who are diabetic know they can't lose their focus on keeping it in check. And technology is making it easier to monitor the disease from home.

More than 520,000 Washingtonians have been diagnosed with diabetes.

Dr. Mamatha Palanati is the medical diabetes program director for Kaiser Permanente Washington. She said the disease needs to be managed closely, because it can lead to serious health complications.

Palanati noted that fortunately, people don't need to leave their homes to do this in some cases.

"In today's world, there's a much easier way to do it, like telehealth," said Palanati. "Telehealth provides multiple ways for the follow-up and connection to the health care for any individual."

Palanti said people managing diabetes still should plan to see their physician in person at least once a year. Management of other factors, like blood pressure and cholesterol, can also help reduce complications.

Palanati said monitoring technology can also assist people.

"The family members and caregivers, or anyone who can take care of that particular individual," said Palanati, "can do it remotely and manage their diabetes in a much better way."

Palanati stressed that diabetes is a chronic disease.

"Don't look at this as an additional chore or anything," said Palanati. "Make it as a part of your life. So, be active, making sure you adapt to the healthy lifestyles. It may not be perfect, but try your best to get what you can do."




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As World AIDS Day turns 35, the mother of an Indiana teen who became the public face of the disease is a reminder of the importance of never forgetting the hard work of medical researchers and the victims lost in the frenzy to find a cure.

More than 40 million people have died from AIDS, including Ryan White, who grew up in central Indiana at a time when not much was known about it and medicine offered few treatments. Ryan contracted the disease during a blood transfusion at age 13. He became a staunch advocate against discrimination and helped change how Americans view AIDS.

Jeanne White-Ginder, who eventually left Indiana for Florida, said it is imperative to remember all the lost lives.

"That is so important that we remember all the people who got us to where we are today, because they are no longer here," White-Ginder noted. "And I'm not just talking about Ryan, because Ryan was a face, but there are so many people that did all the work."

Just five weeks after Ryan's death in 1990, Congress overwhelmingly passed the Ryan White CARE Act with bipartisan support. The legislation helps more people get tested for HIV and offers assistance to patients in all stages of the disease.

Ryan's mom emphasized AIDS affects people across the spectrum, regardless of labels.

"A gay person has it, a straight person has it, a blood transfusion person has it; it was for everybody," White-Ginder explained. "Once you have AIDS, you're just like everybody else who has AIDS; you're fighting to stay alive. And people fought to stay alive, and people dedicated their lives to get us to where we are today."

She added Ryan would have turned 52 next week.

His mom plans to travel to Indiana University on his birthday, where the Rural Center for AIDS/STD Prevention will present the Ryan White Distinguished Leadership Award to Dr. Joe and Sarah Ellen Mamlin.


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