Researchers at Colorado State University are making headway in identifying how osteoarthritis progresses in horses, and their findings could one day also help people who develop the degenerative disease after injuring a knee, elbow or shoulder.

Lynn Pezzanite, doctor of veterinary medicine and assistant professor at Colorado State University, said the disease affects nearly eight in ten horses over age 15.

"It's the most common disorder affecting joints in horses, as well as in people, and one of the most common disorders that we treat overall in horses. It's one of the most common reasons horses present to a veterinarian," she said.

Pezzanite and her team are hoping to find markers of how osteoarthritis develops in horses by studying individual immune cells in joint fluid. Those markers may provide insights on how veterinarians can use gene therapies or other treatments at specific stages to slow the disease's progression.

Typically, people and animals only show signs of osteoarthritis at advanced stages, when they experience joint pain. Pezzanite believes information in immune cells might expose the disease much earlier, even before evidence appears on X-rays.

"Our goal with this work is to look at those very early stages in horses that have post-traumatic arthritis, so that we can determine that tipping point of when we should be intervening or not. And hopefully this will inform treatment in humans as well," she continued.

Pezzanite said people could benefit from this research if the immune markers can be translated across species. Physicians would have better information about when to intervene before full-blown osteoarthritis develops.

"If you're playing soccer and twist your knee, tear your ACL, we would potentially be able to take a sample of that joint fluid and know whether you're going to develop arthritis or not," she explained. "Which would allow us to be more aggressive in treatment of that joint."

Pork producers are expected to argue against California's animal welfare laws at a hearing Wednesday before the House Committee on Agriculture.

The witnesses all oppose California's Proposition 12, which establishes minimum space requirements for egg-laying hens and breeding pigs and bans the sale of products failing to comply with those standards.

Wayne Pacelle, president of the advocacy group Animal Wellness Action, said factory farms have too much influence on the federal government.

"The American public doesn't support confining an animal so severely that she can't even turn around," Pacelle asserted. "These crates and cages that they jam breeding sows and laying hens into don't give the animals any opportunity to move."

Across the country, 1,200 producers already comply with Proposition 12 and currently supply pork and eggs to California, according to a report released this week by Animal Wellness Action.

Last week, the Department of Justice sued the State of California, seeking to invalidate parts of Proposition 12, arguing the standards are expensive to implement and drive up the cost of eggs.

Pacelle noted avian flu reduced the supply of eggs and drove up prices. He added California pork and egg producers have already spent millions to comply with Proposition 12.

"The egg producers in California want to keep that law," Pacelle contended. "They don't want to be undercut by cheap eggs coming from Mexico or Iowa, where the animals are jammed, wing to wing, shoulder to shoulder, and can't even move. I mean, giving the animal space may cost a couple of pennies more, but it's what's right."

Congress is considering whether the next Farm Bill should include a proposal to invalidate many state animal welfare laws. The Food Security and Farm Protection Act would overturn Proposition 12 and similar laws in other states.


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A new "Compassion Calculator" launched by the charity portal FarmKind aims to help Coloradans who eat meat improve their animal welfare footprints by funneling small donations to verified nonprofits, similar to how polluting companies buy offsets to reduce their carbon footprints.

Thom Norman, cofounder of FarmKind, said the calculator makes it easy for anyone to help end the controversial practice of factory farming, where large numbers of animals are confined in small spaces to produce dairy, eggs and meat as cheaply as possible.

"Most people agree that factory farming is bad, almost half of people in America say that they want to see a ban on new factory farms," Norman reported. "But people often don't know what they can do to help with this problem."

Proponents of factory farming have argued it is necessary to meet growing demand from a rising global population but Norman believes the marketplace is shifting. One recipient of the donations, The Humane League, led successful campaigns to get McDonald's, Panera, Starbucks and Taco Bell to stop using eggs from hens confined in cages so small, birds could not stretch their wings or stand upright.

The shift to cage-free eggs has accelerated after 11 states, including Colorado, set regulations on so-called conventional eggs and the recent bird flu crisis, which led to the loss of more than 125 million U.S. hens.

Norman argued the crowded, high stress conditions in cages are not only inhumane, they also present a clear risk of rapid disease transmission.

"It also is a major driver of public health risks, like for example, antibiotic resistant diseases," Norman stressed. "We feed three quarters of all antibiotics to animals."

FarmKind recently announced its first partnership with a major restaurant chain to use the calculator at scale. Animal welfare effects are offset by three cents per hamburger, and just two cents for an omelet. Norman estimated a three cent offset on last year's global burger sales, less than the cost of a ketchup packet, would have generated nearly $80 million to help create a more humane food system.


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Minnesota's transition to the warmer months has been rough when factoring in air quality.

Just like in 2023, there are occasional bouts of unhealthy smoke from Canadian wildfires and animal experts said pets need protection, too. The American Humane Society said just like their owners, the respiratory systems of dogs and cats can suffer when smoky conditions come on strong.

Dr. Thomas Edling, chief veterinary officer of the Humane Society, said dogs need their outside time on a daily basis but when the air quality is bad, it should to be limited to mainly bathroom breaks. He discussed complications with dogs unable to resist running around.

"Younger dogs, especially, are very prone to doing that," Edling observed. "And when do that, you just make the situation worse, because you are breathing more air in quickly, more particulate matter, things like that."

He added owners should avoid activities like playing fetch during brief outdoor moments with their dog. The Humane Society said older pets and certain breeds, including French bulldogs and pugs, are more susceptible to poor air quality and require extra vigilance.

Edling echoed guidance from other health experts who said when the air is filled with smoke, pet owners should keep their windows and doors closed. If a pet's food and water bowl is normally placed outside, they need to be brought in.

"Those will be a collection point for the particulate matter in the air as it falls down and that debris will contaminate the food and the water," Edling pointed out.

After any outdoor activity, owners are encouraged to monitor their pet for coughing, sneezing and difficulty breathing. If the animal shows signs it breathed in too much unhealthy air, a veterinarian should be consulted for possible treatment.


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