Wayne State University has received an $11 million grant from the National Institutes of Health to investigate how volatile organic compounds contribute to preterm births.

The five-year grant will be used to fund the Center for Leadership in Environmental Awareness and Research, where scientists will study the link between volatile organic compounds and preterm births in the City of Detroit.

One goal is to create new ways to pinpoint the sources of industrial pollutants, and develop ways to mitigate their negative health effects.

Carol Miller, professor of civil and environmental engineering and co-leader of the program at Wayne State University, said the ultimate goal is healthier moms and babies.

"Very specifically, we're looking at how those contaminants impact women of childbearing age, and may be a factor influencing the high preterm birthrate in the Detroit area," Miller explained.

Preterm births occur before 37 weeks, often leaving infants with breathing and feeding issues, developmental delays, or problems with seeing and hearing. According to the March of Dimes, among large American cities, Detroit has the highest rate of preterm births, at 14.6%.

Volatile organic compounds are toxic vapors or gases, mostly generated by industrial sites. There are hundreds of contaminated sites in Detroit, and researchers theorize the effects of the compounds contribute to Detroit's high preterm birthrate.

Dr. Melissa Runge-Morris, professor of oncology at and co-leader of the program, said preterm births most often occur in marginalized communities.

"We are particularly plagued by environmental health disparities that affect and impact the most vulnerable members of our urban community," Runge-Morris emphasized.

A parallel goal of the study is to develop new technology for detecting the location and source of volatile organic compounds to help develop a program to mitigate their health effects. Runge-Morris said the team of 31 researchers includes engineering and biomedical scientists, educators and community partners.

"A lot of what we're doing is what would be called sort of 'big data' analysis, to evaluate large numbers of sensors," Runge-Morris noted. "To figure out not only home-by-home, but certain neighborhoods."

It's the time of year when people start thinking about spring cleaning and lawn care - which also means more exposure to health risks from products they may not think of as poisons.

Nearly every Indiana household is full of items that can be lethal - from bug spray to hairspray, and furniture polish to lawn fertilizer.

Stored improperly, some products can cause injury or even death if anyone ingests, smells, or spills them on skin or clothing.

Dr. Blake Froberg - medical director at the Indiana Poison Center - said liquids like antifreeze and window-washer fluid may look like sports drinks to young kids, and can have some very harmful effects.

"Certain lamp oils," said Froberg, "with the summer coming up, a lot of people will have tiki torches. And that lamp oil that's used in tiki torches - to a young child, that can look like apple juice - can have very harmful effects to somebody's lungs if they get into that."

Symptoms of poisoning include nausea, vomiting, diarrhea and rashes.

The Indiana Department of Health suggests storing household chemicals with proper labeling and tight lids, and periodically checking those containers. Froberg added that they should be in locked cabinets inaccessible to kids.

America's Poison Centers data show in Indiana, a poisoning case is reported about every 11 minutes.

Medications can also be dangerous, with nearly 68,000 cases of kids ingesting basic analgesics or painkillers in one recent year, nationally.

Froberg said it isn't just prescription drugs to be concerned about.

"Acetaminophen, which is often sold as Tylenol," said Froberg, "aspirin, diphenhydramine, often sold as Benadryl. So, you want to pay attention to not only your prescription medications, but also the over-the-counter medications."

Froberg pointed out that child-resistant caps on medications may slow them down, but given enough time, a child can figure out how to remove them.

America's Poison Centers data show 44% of Indiana children age 5 or younger have been involved in a poison-related incident - and 95% of those occur at home.




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National Poison Prevention Week is coming up, and the staff at the Illinois Poison Center is getting the word out to be aware of toxic substances around the house.

The nonprofit organization provides both assistance and education on what to do if you suspect poisoning, and courses on identifying poisonous substances.

Last year, the center handled nearly 70,000 involving potentially harmful substances, ranging from minor to severe.

Dr. Michael Wahl, medical director for the center, said almost 40% of those cases involved children age five or younger.

"This is kind of the hallmark week for us to get the word out of the importance of poison prevention planning in the house, in the home, to prevent those unintentional ingestions or exposures to potentially harmful products," Wahl explained.

Wahl pointed out the Illinois center was one of the first of its kind in the nation and has been a resource for almost 70 years. It is staffed 24 hours, seven days a week, every day of the year, and can be reached at 800-222-1222.

Wahl noted the center deals with many substances, including drug overdoses, medication errors or reactions, plants, household chemicals, automotive products, insect stings and bites, lead, carbon monoxide and more.

He added the most dangerous time for children can be a visit from a grandparent.

"We recommend keeping the medications in their original containers and childproof caps," Wahl emphasized. "But grandparents will often keep their medications in pill minders. Those are not in child-resistant caps, and it is not uncommon that kids will get into them."

The center provides helpful information and guides, including stickers and refrigerator magnets with its toll-free number, at no charge. But Wahl stressed for those who need immediate help, there are experts standing by.

"Our line is staffed by nurses and pharmacists, so it is medical professionals -- they're not volunteers -- and they are specially trained in medical toxicology, to really answer and help with recommendations on a wide variety of potentially harmful exposures," Wahl emphasized.


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Most Texans take breathing for granted - unless the air is polluted. It's a health issue the Biden administration hopes to mitigate through new restrictions on one of the deadliest air pollutants - soot.

The Environmental Protection Agency wants to tighten national air-quality standards for soot - also known as fine particulate pollution - which haven't been updated since 2012.

Texas is among the top five states for soot pollution, but Elena Craft, senior director, Climate and Health at the Environmental Defense Fund, said a national solution is needed.

"It really impacts every community across the country," she said. "It is harmful because of its contribution to heart ailments, lung disease, asthma attacks - even cancer."

The EPA's rule would reduce the limit on industrial fine soot particles from an annual average of 12 micrograms per cubic meter of air to between nine and 10 micrograms. Public feedback on the proposed new rules is being accepted through March 28.

Soot pollution comes from power plants, vehicles and refineries, and Craft said it's more concentrated in certain parts of Texas than others.

"Houston, Dallas, El Paso - you do see higher ambient concentrations of particulate matter in some of the larger metropolitan areas, for sure," she said, "and also in some of the industrial areas - so, along the ship channel and the Gulf Coast."

Craft said there are also disparities as to who is most affected by soot pollution - with communities of color more likely to live near industrial facilities, railyards and other polluting facilities. She said it's also an issue for children.

"They breathe more air per pound of body weight than an adult," she said, "and so they are at higher risk, as well as the elderly."

According to Craft, the new standards proposed by the EPA are a welcome improvement, but the Environmental Defense Fund would like to see even stricter rules. The standards are expected to be finalized this summer.