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Conservationists tout Indiana's old mines and brownfields to develop renewable energy; Louisiana becomes 1st state to require the display of the Ten Commandments in public schools; Black Hills Visitor Center under new joint tribal, federal oversight; Judge set to rule on massive MT logging project.

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Former President Donald Trump says he loves Milwaukee, civil rights groups reject designated protest zones for the RNC convention and a New York Equal Rights Amendment is restored to the November ballot.

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Rural educators say they need support to teach kids social issues, rural businesses can suffer when dollar stores come to town, prairie states like South Dakota are getting help to protect grasslands and a Minnesota town claims the oldest rural Pride Festival.

Iowa Researchers Discover Better Stroke Treatment Options

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Thursday, May 25, 2023   

Researchers at the University of Iowa are using one of the body's naturally occurring waste products to treat stroke, potentially lessening the damage.

Uric acid is a natural biological component of human blood, improving flow in the smaller vessels and reducing brain damage by neutralizing chemicals occurring during a stroke. But because the uric acid is quickly consumed by the body during a stroke, there is not enough left in the bloodstream to fully prevent brain damage.

Dr. Enrique Leira, professor of vascular neurology at the University of Iowa and a research leader, said scientists are introducing uric acid back into the bloodstream to block something called oxidative stress.

"We know the uric acid we have as humans helps us with this problem, but it's not enough," Leira explained. "That's why the rationale is to supplement patients that are having an acute stroke with additional uric acid through their veins in order to block that oxidative stress."

Leira pointed out wide scale clinical trials are next, with the help of the National Institutes of Health, during which doctors hope to be able to completely unblock blood vessels in a patient having a stroke, further limiting the potential damage it can do.

Leira noted using uric acid to protect brain tissue during a stroke could add to the effects of standard treatments to remove blood clots, and could make an especially big difference in rural areas where treatment has been lacking; potentially saving even more lives in underserved areas and putting a dent in a huge problem.

"We have 800,000 strokes per year in the United States, and it is the main cause of disability," Leira emphasized. "In addition to opening the arteries of patients with procedures like we can do now, we need chemical, medical treatments that can boost their outcomes of these patients and result in lesser disability."

Stroke is also among the leading causes of death in the U.S., and Leira said rapid treatment can often mean protecting brain cells, improving patient outcomes and potentially saving lives.

References:  
Stroke Facts CDC 2023

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