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Pentagon announces another boat strike amid heightened scrutiny; An End to Hepatitis B Shots for All Newborns; DeWine veto protects Ohio teens from extended work hours; Wisconsin seniors rally for dignity amid growing pressures; Rosa Parks' legacy fuels 381 days of civic action in AL and the U.S.

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Trump escalates rhetoric toward Somali Americans as his administration tightens immigration vetting, while Ohio blocks expanded child labor hours and seniors face a Sunday deadline to review Medicare coverage.

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Native American tribes are left out of a new federal Rural Health Transformation Program, cold temperatures are burdening rural residents with higher energy prices and Missouri archivists says documenting queer history in rural communities is critical amid ongoing attacks on LGBTQ+ rights.

Iowa Researchers Discover Better Stroke Treatment Options

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Thursday, May 25, 2023   

Researchers at the University of Iowa are using one of the body's naturally occurring waste products to treat stroke, potentially lessening the damage.

Uric acid is a natural biological component of human blood, improving flow in the smaller vessels and reducing brain damage by neutralizing chemicals occurring during a stroke. But because the uric acid is quickly consumed by the body during a stroke, there is not enough left in the bloodstream to fully prevent brain damage.

Dr. Enrique Leira, professor of vascular neurology at the University of Iowa and a research leader, said scientists are introducing uric acid back into the bloodstream to block something called oxidative stress.

"We know the uric acid we have as humans helps us with this problem, but it's not enough," Leira explained. "That's why the rationale is to supplement patients that are having an acute stroke with additional uric acid through their veins in order to block that oxidative stress."

Leira pointed out wide scale clinical trials are next, with the help of the National Institutes of Health, during which doctors hope to be able to completely unblock blood vessels in a patient having a stroke, further limiting the potential damage it can do.

Leira noted using uric acid to protect brain tissue during a stroke could add to the effects of standard treatments to remove blood clots, and could make an especially big difference in rural areas where treatment has been lacking; potentially saving even more lives in underserved areas and putting a dent in a huge problem.

"We have 800,000 strokes per year in the United States, and it is the main cause of disability," Leira emphasized. "In addition to opening the arteries of patients with procedures like we can do now, we need chemical, medical treatments that can boost their outcomes of these patients and result in lesser disability."

Stroke is also among the leading causes of death in the U.S., and Leira said rapid treatment can often mean protecting brain cells, improving patient outcomes and potentially saving lives.

References:  
Stroke Facts CDC 2023

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